Moiety (chemistry)

Benzyl acetate contains a benzyloxy moiety (encircled with light orange). It also contains an ester functional group (in red), and an acetyl functional group (encircled with dark green). Other divisions can be made.

In organic chemistry, a moiety (/ˈmɔɪəti/ MOY-ə-tee) is a part of a molecule[1][2] that is given a name because it is identified as a part of other molecules as well.

Typically, the term is used to describe the larger and characteristic parts of organic molecules, and it should not be used to describe or name smaller functional groups [1][2] of atoms that chemically react in similar ways in most molecules that contain them.[3] Occasionally, a moiety may contain smaller moieties and functional groups.[citation needed]

A moiety that acts as a branch extending from the backbone of a hydrocarbon molecule is called a substituent or side chain, which typically can be removed from the molecule and substituted with others.

The term is also used in pharmacology, where an active moiety is the part of a molecule responsible for the physiological or pharmacological action of a drug.

  1. ^ a b IUPAC, Compendium of Chemical Terminology, 2nd ed. (the "Gold Book") (1997). Online corrected version: (2006–) "moiety". doi:10.1351/goldbook.M03968
  2. ^ a b "Illustrated Glossary of Organic Chemistry - Moiety". web.chem.ucla.edu. Retrieved 2017-04-22.
  3. ^ IUPAC, Compendium of Chemical Terminology, 2nd ed. (the "Gold Book") (1997). Online corrected version: (2006–) "functional group". doi:10.1351/goldbook.F02555

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